A client taking lisinopril (Prinivil) reports a persistent dry cough. What should the nurse convey to the client?

A persistent dry cough is a notable and established side effect associated with the use of lisinopril, which is an ACE (angiotensin-converting enzyme) inhibitor. The mechanism behind this side effect involves the accumulation of bradykinin, a peptide that increases as ACE inhibitors prevent its breakdown. This accumulation can lead to the stimulation of cough receptors in the respiratory tract, resulting in a dry cough.

Patients on lisinopril should be informed that while this cough can be bothersome, it is not indicative of a serious condition and is, in fact, a recognized effect of the medication. Understanding this helps patients manage their expectations and allows for better communication with healthcare providers regarding their symptoms.

Discussing the cough as a side effect helps the patient comprehend that this is a well-documented outcome and may not necessarily warrant immediate concern, although they should notify their healthcare provider if the cough persists or becomes intolerable, potentially leading to a change in medication.