During the administration of intravenous amphotericin B (Fungizone), what should the nurse monitor in the client?

Monitoring urine output during the administration of intravenous amphotericin B is crucial because this medication can have nephrotoxic effects. Amphotericin B is known to cause damage to renal tubules and may lead to acute kidney injury. As a result, assessing urine output helps evaluate kidney function and detect potential complications early on. A decrease in urine output could indicate that the kidneys are being adversely affected by the drug, prompting the need for further evaluation and potential intervention.

In addition to monitoring urine output, tracking other parameters like blood pressure, heart rate, and temperature can also be important for general patient safety and assessing overall health status. However, the direct relationship between amphotericin B and renal function makes monitoring urine output particularly critical in this scenario.