What should a nurse do when preparing epoetin alfa (Epogen) from a single-use vial?

When preparing epoetin alfa (Epogen) from a single-use vial, the correct approach is to draw up the required amount of medication and discard any unused portion. This is because epoetin alfa is provided in single-use vials to prevent contamination and ensure the integrity of the medication. The manufacturer recommends that any remaining solution in a single-use vial should not be stored for later use, as this can increase the risk of infection or degradation of the drug, compromising its safety and efficacy.

Using the entire vial for later use is inappropriate due to the risk associated with contamination and stability of the medication. Discarding the entire vial after a single use does not account for the proper drawing and discarding process that should take place in a clinical setting. Refrigerating any unused portions also presents the issue of stability and potential contamination, as once the vial is accessed, it cannot be guaranteed to be sterile after that point.

By following the proper protocol of discarding any unused medication after drawing it up, the nurse ensures the highest level of safety and effectiveness in administering epoetin alfa to the patient.