Which of the following is a major concern with intravenous therapy?

The major concern with intravenous therapy is the risk of infection and phlebitis. Intravenous therapy involves inserting a catheter into a vein, which can create a potential entry point for pathogens. This invasive procedure increases the likelihood of both localized infections at the site of insertion and systemic infections, which can be particularly serious if bacteria enter the bloodstream.

Phlebitis, which is inflammation of the vein, can also occur due to irritation from the intravenous solution or the catheter itself. Both infection and phlebitis are critical complications that can lead to severe health issues, requiring close monitoring and prompt intervention.

While monitoring drug interactions, patient hydration status, and drug absorption rates are important components of patient care and pharmacological management, they do not carry the immediate, acute risks associated with the physical insertion of an IV line. The risk of infection and phlebitis is a direct complication arising from the invasive nature of intravenous therapy, making it a top concern for healthcare providers.